CS2220: Introduction to Computational Biology
Instructors: Wong Limsoon, Li Xiaoli, and Feng Mengling / 2015/2016 Semester 1 / IVLE

• Lecture is held every Thursday @ 9am in SR@LT19
• Tutorial is integrated into the lecture
• Main references: The Practical Bioinformatician (by Wong, WSPC) and Algorithms in Bioinformatics: A Practical Introduction (by Sung, CRC).

• The goals of CS2220 (Introduction to Computational Biology) are: (1) development of flexible and logical problem solving skills; (2) understanding of main bioinformatics problems; and (3) appreciation of main techniques and approaches to bioinformatics. To achieve the goals above, we expose the students to a series of case studies spanning gene feature recognition, gene expression and proteomic analysis, gene finding, sequence homology interpretation, phylogeny analysis, physical mapping, and genome sequencing

• Click here for related courses offerred in SOC

Lecture Slides, Assignments, and Notes

• Course Briefing, 13/8/15 (by WLS)
  Readings: Chapter 1 of The Practical Bioinformatician and Chapter 1 of Algorithms in Bioinformatics
  

  
  
  
  

• Unit 1: Essence of Knowledge Discovery, 13/8/15 (by LXL)
  Readings: Chapter 3 of The Practical Bioinformatician

  
  
  
  

• Unit 2: Essence of Knowledge Discovery, 20/8/15 (by LXL)
  Readings: Chapter 3 of The Practical Bioinformatician and Li & Wong, PKDD04, tutorial notes

  
  
  
  

• Unit 3: Gene Feature Recognition, 27/8/15 (by WLS)
  Readings: Chapter 4 and chapter 7 of The Practical Bioinformatician, and Koh & Wong, GIW2007, pp 73-82
  Assignment: Assignment #1 (due on 17/9/2015) and translation initiation sites data sets

  
  
  

• Unit 4: Gene Expression Analysis, 10/9/15 & 17/9/15 (by LXL)
  Readings: Chapter 14 of The Practical Bioinformatician
  Assignment: Assignment #2 (due on 8/10/2015) and gene expression data sets

  
  
  
  

• Unit 5(a): Single-Nucleotide Polymorphisms, 1/10/15 (by FML)
  Unit 5(b): Genome-Wide Association Studies, 8/10/15 (by FML)
  Project: Project descriptions (due on 12/11/2015)

  
  
  
  

• Unit 6: Essence of Sequence Comparison, 15/10/15 & 22/10/15 (by WLS)
  Readings: Chapter 10 of The Practical Bioinformatician and Chapters 2 & 5 of Algorithms in Bioinformatics
  Assignment: Assignment #3 (due on 5/11/2015)

  
  
  
  

• Unit 7: Sequence Homology Interpretation, 22/10/15 & 29/10/15 (by WLS)
  Readings: Chapter 19 of The Practical Bioinformatician

  
  
  
  

• Unit 8: Gene Finding, 5/11/15 (by WLS)
  

  
  
  
  

• Unit 9: Phylogenetic Trees, 12/11/15 (by WLS)
  Readings: Chapter 19 of The Practical Bioinformatician and Chapters 7 & 8 of Algoritms in Bioinformatics