CS2220: Introduction to Computational Biology
Instructors: Wong Limsoon and Li Xiaoli / 2016/2017 Semester 1 / IVLE

• Lecture is held every Thursday @ 9am in SR@LT19
• Tutorial is integrated into the lecture
• Main references: The Practical Bioinformatician (by Wong, WSPC) and Algorithms in Bioinformatics: A Practical Introduction (by Sung, CRC).

• The goals of CS2220 (Introduction to Computational Biology) are: (1) development of flexible and logical problem solving skills; (2) understanding of main bioinformatics problems; and (3) appreciation of main techniques and approaches to bioinformatics. To achieve the goals above, we expose the students to a series of case studies spanning gene feature recognition, gene expression and proteomic analysis, gene finding, sequence homology interpretation, phylogeny analysis, physical mapping, and genome sequencing

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Lecture Slides, Assignments, and Notes

• Course Briefing, 11/8/16 (by LXL)
  Readings: Chapter 1 of The Practical Bioinformatician and Chapter 1 of Algorithms in Bioinformatics
  

  
  
  
  

• Unit 1: Essence of Knowledge Discovery, 11/8/16 & 18/8/16 (by LXL)
  Readings: Chapter 3 of The Practical Bioinformatician and Li & Wong, PKDD04, tutorial notes

  
  
  
  

• Unit 2: Gene Expression Analysis, 25/8/16 & 1/9/16 (by LXL)
  Readings: Chapter 14 of The Practical Bioinformatician
  Assignment: Assignment #1 (due on 29/9/2016) and gene expression data sets

  
  
  
  

• Unit 3: Gene Feature Recognition, 8/9/16 & 15/9/16 (by WLS)
  Readings: Chapter 4 and chapter 7 of The Practical Bioinformatician, and Koh & Wong, GIW2007, pp 73-82
  Assignment: Assignment #2 (due on 13/10/2016) and translation initiation sites data sets

  
  
  

• Unit 4: Essence of Sequence Comparison, 29/9/16 & 6/10/16 (by WLS)
  Readings: Chapter 10 of The Practical Bioinformatician and Chapters 2 & 5 of Algorithms in Bioinformatics
  Assignment: Assignment #3 (due on 3/11/2016)

  
  
  
  

• Unit 5: Sequence Homology Interpretation, 13/10/16 (by WLS)
  Readings: Chapter 19 of The Practical Bioinformatician

  
  
  
  

• Unit 6: Gene Finding, 20/10/16 & 27/10/16 (by WLS)
  

  
  
  
  

• Unit 7: Phylogenetic Trees, 3/11/16 (by WLS)
  Readings: Chapter 19 of The Practical Bioinformatician and Chapters 7 & 8 of Algoritms in Bioinformatics